WebMunehisa Shimamura is an academic researcher from Cornell University. The author has contributed to research in topic(s): Ischemia & Receptor. The author has an hindex of 5, co-authored 5 publication(s) receiving 331 citation(s). Previous affiliations of Munehisa Shimamura include Center for Neural Science. WebAug 11, 2009 · Together, these results reveal an important signaling pathway controlling CD36-mediated foam cell formation/cardiovascular diseases, and findings that TR4 …
Co-operation of TLR4 and raft proteins in LPS-induced pro
WebMar 13, 2014 · CD36 was first described as a thrombospondin receptor and as a receptor for other molecules containing the thrombospondin-type repeat domain [ 96 ]. The CD36 receptor consists of an extracellular domain and two cytoplasmic fragments containing the C-terminal and N-terminal domains [ 97 ]. WebJan 23, 2007 · Upon ligand binding, such as oxLDL or amyloid-beta 42, interacts with the heterodimer TLR4:TLR6, the complex is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as … former name of chennai dan word
Functional consequences of CD36 downregulation by TLR signals
WebMar 1, 2024 · OxLDL mediated DPP4 up-regulation was considerably diminished by Toll-like receptor-4 (TLR4) knockdown and CD36 deficiency. TRIF deficiency, but not MyD88 deficiency, attenuated oxLDL-induced DPP4 increase. Interpretation Our study suggests a key role for oxLDL and downstream CD36/TLR4/TRIF in regulating DPP4 expression. WebOct 22, 2014 · The TRIF-dependent signaling is linked with endocytosis of the activated TLR4, which is controlled by CD14. In addition to CD14, other raft proteins like Lyn tyrosine kinase of the Src family, acid sphingomyelinase, CD44, Hsp70, and CD36 participate in the TLR4 signaling triggered by LPS and non-microbial endogenous ligands. WebApr 6, 2024 · 生技一文献翻译作业3.第三组.pdf,缺氧可调节人成熟树突状细胞免疫调节受体的 表达谱: 识别 TREM-1 作为一种新型缺氧标记物在体外和体内的研究 (承担分工:1.标题、介绍、方法及图1: , ,生物技术1 班 2.结果以及中间的图2~ 图7,整理: , ,生物技术1 班 3.讨论: , ,生物技术1 班) 树突状细胞 ... former name of ciudad bolivar