Stem cell-based therapy for malignant glioma
網頁Stem cell-based therapy for malignant glioma Daniel Bexell a,b, ⇑ , Andreas Svensson a,c , Johan Bengzon a,c,d a Lund Stem Cell Center, BMC B10, Lund University, Lund, … 網頁Glioblastoma is a devastating grade IV cancer that affects the central nervous system and the spinal cord primarily in older adults but can also affect youth. The progression of the …
Stem cell-based therapy for malignant glioma
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網頁Because the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills tumor cells, it is one of the most promising candidates for cancer treatment. TRAIL … 網頁2008年2月3日 · Various studies have demonstrated the tremendous tropism of stem cells for malignant gliomas, making these cells a potential vehicle for delivery of therapeutic genes to disseminated glioma cells. However, little is known about the mechanisms underlying the glioma-induced tropism of stem cells. Soluble factors including …
網頁2024年8月30日 · His research demonstrated the existence of a novel miR1983-TLR7-IFNβ circuit that licenses NK cells to kill glioma cells ... The emphasis here is focused on nanotechnology-based therapies that ... 網頁Glioblastoma, the most common and most malignant type of primary brain tumor, is associated with poor prognosis, even when treated using combined therapies, including …
網頁2024年9月10日 · 1 INTRODUCTION Glioblastoma is characterized by diffuse infiltration into the normal brain parenchyma. 1, 2 Remarkable invasiveness is responsible for its recurrence after surgical resection. In addition to differentiated glioma cells, the …
網頁2024年4月1日 · As normal stem and progenitor cells participate in tissue development and repair, these developmental programs re-emerge in CSCs to support the development and progressive growth of tumors. Elucidation of the molecular mechanisms that govern CSCs has informed the development of novel targeted therapeutics for GBM and other brain …
網頁Translation of novel therapies for brain cancer into clinical practice is of the utmost importance as primary brain tumors are responsible for more than 200,000 deaths worldwide each year. While many research efforts have been aimed at improving survival rates over the years, prognosis for patients with glioblastoma and other primary brain tumors … nereus father網頁Detaljer MARC Bexell, Daniel, 1978-(författare) Stem cell based therapy of malignant brain tumors : mesenchymal and neural precursor cells as migratory vehicles in experimental gliomas / by Daniel Bexell Bok Avhandling Engelska 2008 Förlag, utgivningsår nereus how to say網頁2024年10月26日 · Glioma is the most common malignant primary brain tumor diagnosed in adults. Current therapies are unable to improve its clinical prognosis, imposing the need for innovative therapeutic approaches. The main reason for the poor prognosis is the great cell heterogeneity of the tumor and its immunosuppressive microenvironment. Development … its remodeling網頁The anionic cobaltabis (dicarbollide) [3,3′-Co(1,2-C2B9H11)2]−, [o-COSAN]−, is the most studied icosahedral metallacarborane. The sodium salts of [o-COSAN]− could be an ideal candidate for the anti-cancer treatment Boron Neutron Capture Therapy (BNCT) as it possesses the ability to readily cross biological membranes thereby producing cell cycle … nereus supply chain網頁2024年7月8日 · Introduction Malignant gliomas are the most frequent and lethal cancers originating in the central nervous system (), and include three main high-grade glioma phenotypes based on genome-wide expression profiling and DNA methylation analysis in recent clinical assessments: proneural, mesenchymal, and classical (2, 3).). itsrecycled picnic tables網頁Stem cell based therapy of malignant brain tumors : mesenchymal and neural precursor cells as migratory vehicles in experimental gliomas / by Daniel Bexell Bexell, Daniel, 1978- (författare) ISBN 9789186059767 Lund : Lund University, 2008 Engelska 136 s. Serie: Lund University, Faculty of Medicine doctoral dissertation series, 1652-8220 ; 2008:123 its refers to網頁Stem cells can be used to establish a long-term antitumor response by stimulating the immune system and delivering prodrug, metabolizing genes, or oncolytic viruses. In this … nereus shipping fleet